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Identical coursesPharmacology and Pharmacokinetics (B-KUL-E07U0A)
Cannot be taken as part of an examination contract
Vankelecom Hugo (coordinator) | Casteels Minne | Ulens Chris | Vankelecom Hugo | de Hoon Jan Aims
After completing this course unit, students have insight into the mode of action of different classes of drugs. Students can situate and assimilate new information within the framework that is provided during the lectures. Finally, they have acquired knowledge of the process of development, of evaluation and testing, the main therapeutic classes, their MoA, main side effects and use.
Previous knowledge
Cell biology, biochemistry, pathophysiology, basics of pathology and anatomy are essential prior knowledge for this course.
Order of Enrolment
Mixed prerequisite:
You may only take this course if you comply with the prerequisites. Prerequisites can be strict or flexible, or can imply simultaneity. A degree level can be also be a prerequisite.
Explanation:
STRICT: You may only take this course if you have passed or applied tolerance for the courses for which this condition is set.
FLEXIBLE: You may only take this course if you have previously taken the courses for which this condition is set.
SIMULTANEOUS: You may only take this course if you also take the courses for which this condition is set (or have taken them previously).
DEGREE: You may only take this course if you have obtained this degree level.
(FLEXIBLE(E08C0A) OR FLEXIBLE (U01D0A)) AND (FLEXIBLE(E07C9B) OR FLEXIBLE (U01D1A))
The codes of the course units mentioned above correspond to the following course descriptions:
E08C0A : Neurofysiologie
U01D0A : Neurofysiologie
E07C9B : Ontstaansmechanismen van ziekten
U01D1A : Ontstaansmechanismen van ziekten
This course unit is a prerequisite for taking the following course units:
E03N9A : Pharmaceutical Medicine
E07U2A : Toxicology
Is included in these courses of study
- Master of Biomedical Sciences (Leuven) 120 ects.
Activities
7 ects. Pharmacology and Pharmacokinetics (B-KUL-E07U0a)
Content
The following subjects will be covered:
Introduction to pharmacology:
Development (incl. notions of 'rational drug design'); evaluation and testing of new drugs (e.g. bioassay); brief overview of registration procedure and refunding
Pharmacokinetics:
• insights into kinetic processes of absorption, distribution and elimination
• biotransformation/metabolism of drugs
Pharmacodynamics and receptors (basics, since receptor mechanisms are addressed extensively in cell biology and biochemistry)
Toxicology (introductory):
• general principles
• toxicity of drugs: mechanisms
Pharmacology, with special attention to mechanisms of action of the different groups of pharmacological agents (no individual drugs will be discussed) related to:
• the autonomous and peripheral nervous system
• the central nervous system
• the cardiovascular system
• the endocrine system
• pain, fever and inflammation
Oncolytics, biotechnological drugs (monoclonal antibodies)
Course material
Lecture notes, available via Medica, and online via Toledo (after some weeks).
Toledo with literature and references
Toledo will have a list of all course material that is expected knowledge
PowerPoint presentations on Toledo.
Some lectures may be recorded.
Format: more information
Active participation is expected during the lectures.
We aim to provide the ppt on Toledo before the lecture.
Evaluation
Evaluation: Pharmacology and Pharmacokinetics (B-KUL-E27U0a)
Explanation
The full package of "pharmacology and pharmacokinetics" will be examined by one of the lecturers.
Oral exam with written preparation (approx. 30 minutes).
The score is based on your oral answers, and a global score for the total exam is given.
Information about retaking exams
Identical to the first session.