Basics of Biological Chemistry (B-KUL-I0D33A)
Aims
The course 'Basics of Biological Chemistry' is an introductory course. The main objective of the course is to refresh the basic principles of chemistry and to link this knowledge with cellular life at the molecular level
Previous knowledge
Basic knowledge in anorganic and organic chemistry is required.
Order of Enrolment
This course unit is a prerequisite for taking the following course units:
I0D51A : Bioinformatics: High-Throughput Analysis (No longer offered this academic year)
Is included in these courses of study
Activities
4 ects. Basics of Biological Chemistry (B-KUL-I0D33a)
Content
1) The scale of live.
organisms: taxonomy, an evolutionary framework
plant and animal cells: eukaryotes
bacteria: prokaryotes, origin of organelles
organelles: functions
2) Small molecules
the periodic table, highlight the important elements C,N,O,P,S
from atom to molecule, chemical behaviour
electronegativity
oxidation/reduction
ion bonds, cation - anion
hydrogen bonds
chemistry of water, polar-nonpolar,hydrophilic-hydrophobic, pH
3) Large molecules
sugars and polysaccharides
fatty acids, lipids, phospholipids, membranes
amino acids and proteins
nucleotides and nucleic acids
structure/function of DNA
4) Energy and metabolism
thermodynamics
free energy
activation energy
enzymes
ATP/ADP, electron carriers NADH/NADPH
organisation and principles of metabolic pathways
Course material
- Handbook: 'General, Organic, and Biochemistry: Connecting Chemistry to Your Life' Blei, I., Odian, G., W.H. Freeman: New York
- Consult Toledo for slides and more information
Format: more information
- Lectures with exercises
Evaluation
Evaluation: Basics of Biological Chemistry (B-KUL-I2D33a)
Explanation
Students make exercises during the semester that are evaluated.
The content of the lectures is evaluated during the regular examination period. The exam consists of several open questions for which a written answer has to be given.