Lipids in Health and Disease (B-KUL-E0G33A)
Aims
Lipids are of decisive importance for many common diseases, such as cardiovascular diseases (e.g. infarctions), neuronal diseases (e.g. Alzheimer’s disease) and cancer. Lipids are also essential for the function of biomaterials and can be used in drug delivery devices. At the end of this course students will be able to define/explain:
- the role of lipids in human health and disease
- the potential of lipids as disease biomarkers
- the potential of lipid metabolic pathways/enzymes as modulators and targets for therapy
- methods to study lipids
- the application in biomaterials and in drug delivery systems
Previous knowledge
Given the interactive course format, there is a maximum number of students in this course. Students from a Faculty or programme other than Biomedical Sciences can submit a request to take this course.
Students from another program can only be admitted if the maximum number of students has not yet been reached.
General biomedical knowledge
Is included in these courses of study
- Opleidingsonderdelen uitsluitend via creditcontract Faculteit Geneeskunde (Leuven)
- Bachelor in de biomedische wetenschappen (Leuven) 180 ects.
- Bachelor in de biomedische wetenschappen (Kortrijk) 180 ects.
- Bachelor in de biologie (programma voor studenten gestart vóór 2023-2024) (Kortrijk) (Minor humane biologie) 180 ects.
- Bachelor in de biologie (programma voor studenten gestart vóór 2023-2024) (Kortrijk) (Optie Biochemie en Biotechnologie) 180 ects.
- Bachelor in de geneeskunde (programma voor studenten gestart in 2023-2024 of later) (Leuven) 180 ects.
- Bachelor in de geneeskunde (programma voor studenten gestart in 2023-2024 of later) (Kortrijk) 180 ects.
- Bachelor in de biologie (programma voor studenten gestart in 2023-2024 of later) (Kortrijk) (Minor humane biologie) 180 ects.
Activities
3 ects. Lipids in Health and Disease (B-KUL-E0G33a)
Content
1. Course Introduction
2. Biochemistry of lipids
3. Lipids in cardiovascular disease
4. Lipids in chronic kidney disease
5. Lipids in liver disease
6. Lipids in cancer
7. Lipids in brain disease
8. (Sphingo)lipids in neurological diseases
9. Lipid fingerprinting in disease: basic principles of chromatography and mass spectrometry
10. Lipid Imaging and Identification using Mass Spectrometry
11. Lipid-based nano- and micromaterials for diagnosis and therapy
12. Lipids & biomaterials
Course material
PowerPoint presentations will be made available in Toledo
Personal notes: students are encouraged to take notes themselves during classes
Evaluation
Evaluation: Lipids in Health and Disease (B-KUL-E2G33a)
Explanation
-Students are given assignments in preparation of each lecture (reading a review, looking up some literature,…)
-There is a Multiple Choice exam (without correction for guessing) immediately following each lecture. This exam is open book and covers the content of the lecture and the assignment. Students are expected to participate in all sessions. If a student cannot take part in a particular session, he/she will notify the course coordinator in advance and will be given a small assignment instead.
-In addition, students (in small groups) will select a subtopic and present this to their fellow students in a 15 min powerpoint presentation. This presentation will be scored by the course coordinator.