Lipids in Health and Disease (B-KUL-E0G33A)

3 ECTSEnglish18 Second termCannot be taken as part of an examination contract
POC Biomedische wetenschappen

Lipids are of decisive importance for many common diseases, such as cardiovascular diseases (e.g. infarctions), neuronal diseases (e.g. Alzheimer’s disease) and cancer. Lipids are also essential for the function of biomaterials and can be used in drug delivery devices. At the end of this course students will be able to define/explain:

  • the role of lipids in human health and disease
  • the potential of lipids as disease biomarkers
  • the potential of lipid metabolic pathways/enzymes as modulators and targets for therapy
  • methods to study lipids
  • the application in biomaterials and in drug delivery systems

Given the interactive course format, there is a maximum number of students in this course. Students from a Faculty or programme other than Biomedical Sciences can submit a request to take this course.

Students from another program can only be admitted if the maximum number of students has not yet been reached.

General biomedical knowledge

Activities

3 ects. Lipids in Health and Disease (B-KUL-E0G33a)

3 ECTSEnglishFormat: Lecture18 Second term
POC Biomedische wetenschappen

 1. Course Introduction

 2. Biochemistry of lipids

 3. Lipids in cardiovascular disease

 4. Lipids in chronic kidney disease

 5. Lipids in liver disease

 6. Lipids in cancer

7. Lipids in brain disease

8. (Sphingo)lipids in neurological diseases 

9. Lipid fingerprinting in disease: basic principles of chromatography and mass spectrometry

10. Lipid Imaging and Identification using Mass Spectrometry

11. Lipid-based nano- and micromaterials for diagnosis and therapy

 12. Lipids & biomaterials

PowerPoint presentations will be made available in Toledo

Personal notes: students are encouraged to take notes themselves during classes

Evaluation

Evaluation: Lipids in Health and Disease (B-KUL-E2G33a)

Type : Continuous assessment without exam during the examination period
Learning material : None


-Students are given assignments in preparation of each lecture (reading a review, looking up some literature,…)

-There is a Multiple Choice exam (without correction for guessing) immediately following each lecture. This exam is open book and covers the content of the lecture and the assignment. Students are expected to participate in all sessions. If a student cannot take part in a particular session, he/she will notify the course coordinator in advance and will be given a small assignment instead.

-In addition, students (in small groups) will select a subtopic and present this to their fellow students in a 15 min powerpoint presentation. This presentation will be scored by the course coordinator.