Basic Analytical Techniques (B-KUL-X0D00A)
Aims
- Principle concepts of analytical chemistry, i.e. matrix, interferents, selective and specific methods, miscellaneous units of concentration.
- recognition of the general structure of any analytical procedure by identifying the different steps.
- To identify the different types of errors as they occur in analytical processes.
- Being able to describe the origin and consequences of indeterminate errors. Learnig to correctly apply different statistical methods to treat experimental data (evaluation and reporting) in an analytical chemistry context.
- Concentration calculations of complex equilibrium of aqueous solutions: awareness of the limitations and applicability of the obtained results.
- Ionic strength: origin and practical calculation of activities.
- Differences and similarities between different types of discussed titrations.
- Titration curves of complex systems: qualitative and quantitative derivation. Recognition of the different areas of the titration curves and identifying the dominant species.
- Applicability of a titration in relation to the concentration of the analyte and the relevant thermodynamical data.
- Principles of various kinds of chemical indicators and other instrumental techniques to determine the equivalence points. Ability to choose the appropriate method for specific circumstances.
- Being able to describe the physical and chemical principles of the discussed instrumental methods.
- Ability to describe the various components of a specific apparatus concerning its construction, functionality, advantages and limitations.
- for the discussed analytical techniques being able to describe the most relevant applications, advantages and disadvantages compared to other techniques with the purpose to choose the most appropriate technique for a particular analysis.
- Being able to develop and justify a chromatographic analysis on the basis of a demand for analysis of a particular component in a given matrix for a particular purpose. This implies among other things being able to describe and compare the various chromatographic techniques, explain their physical and chemical principles, know the conditions under which a certain chromatographic technique can be applied, know the limitations of the various chromatographic techniques, select the necessary components for performing the various chromatographic techniques
Previous knowledge
Application of stoichiometry on chemical reactions.
Knowledge of the principles of aqueous solutions as a basis for a more elaborate treatment.
Limited practical experience about simple analysis.
Being able to apply elementary concepts of thermodynamics, equilibrium constants, Nernst equation, entropy, free energy, etc.
Basic knowledge of organic chemistry, i.e. function groups, reaction types
Order of Enrolment
This course unit is a prerequisite for taking the following course units:
X0B43B : Laboratory Sessions
I0U12A : Analytical Organic Chemistry
X0D05B : Project Work Bioscience Engineering
G0O48B : Spectroscopy Methods
G0S24A : Advanced Synthesis and Characterization of Molecules and Materials
X0B43C : Laboratory Sessions
X0C51C : Laboratory Sessions: Synthesis and Characterisation
X0B43D : Laboratory Sessions
Identical courses
This course is identical to the following courses:
G0O27A : Analytical Base Technics
I0T52A : Instrumental Analytical Chemistry
X0E52A : Basic Analytical Techniques
Is included in these courses of study
- Bachelor of Chemistry (Programme for students started before 2023-2024) (Kortrijk) (Option: Biochemistry and Biotechnology) 180 ects.
- Bachelor of Chemistry (Programme for students started before 2023-2024) (Kortrijk) (Option: Chemistry) 180 ects.
Activities
4 ects. Lectures and Integrated Exercises I: Analytical Base Technics (B-KUL-X0D00a)
Content
Chapter 1: Analysis strategy
Chapter 2: Errors in chemical analyses
Chapter 3: Sampling and sample preparation
Chapter 4: Complex chemical equilibria
Chapter 5: Acid-base titrations
Chapter 6: Electrochemical methods
Chapter 7: Complexometric titrations
Chapter 8: Spectroscopic methods: basic principles, instrumentation, molecular absorption, fluorescence, atomic spectroscopy
Chapter 9: Gravimetric methods
Course material
textbook and corresponding exercise platform and slides
Is also included in other courses
1.2 ects. Lectures and Integrated Exercises: Chromatography (B-KUL-X0D01a)
Content
- Principle of chromatography
- Column Theory
- Gas chromatography: basic principles and specific properties, theoretical considerations, mobile phase, injectors, detectors, stationary phases, qualitative and quantitative analysis
- HPLC: basic principles and specific properties, theoretical considerations, injectors, detectors, stationary and mobile phase
- Ion chromatography: ion exchange chromatography, ion-pair chromatography, ion suppression chromatography
- exclusion chromatography
Course material
ppt slides
Is also included in other courses
0.8 ects. Laboratory Sessions Analytical Base Technics (B-KUL-X0D02a)
Content
- Determination of the fatty acid profile of margarine
- Soxhlet extraction of methylxanthines from different teas followed by quantitation by ion chromatography
- Determination of vitamin C in fruit (juice) on the basis of a redox titration
- Determination of manganese in a metal alloy by spectrophotometry
Course material
manuals
Is also included in other courses
Evaluation
Evaluation: Basic Analytical Techniques (B-KUL-X2D00a)
Explanation