Basics of Pharmaceutical Technology (B-KUL-H0E19A)

3 ECTSEnglish28 Second termCannot be taken as part of an examination contract
POC Nanowetenschappen en nanotechnologie

The aim of this course is to provide students with a non-pharmaceutical background  a comprehensive introduction to the fundamental concepts and underlying scientific principles of drug formulation, pharmaceutical process development, drug delivery and drug targeting.

Activities

3 ects. Basics of Pharmaceutical Technology (B-KUL-H0E19a)

3 ECTSEnglishFormat: Lecture28 Second term
POC Nanowetenschappen en nanotechnologie

1. Introduction to physicochemical and biopharmaceutical principles underlying drug formulation

   - principles of drug absorption

   - drug dissolution

   - bioavailability and bioequivalence

   - principles of pharmacokinetics

   - transport of drugs across epithelia

2. Disperse systems

   - introductory principles of rheology

   - suspensions

   - emulsions

   - gels

3. Formulation strategies for poorly soluble drugs

   - micro- and nanoparticles

   - cyclodextrine complexes

   - amorphous solid dispersions

   - lipid based drug delivery systems

   - cocrystals

   - colsolvency

4. Agglomeration processes

   - granulation

   - spray drying

   - extrusion-spheronization

5. Principles of controlled drug delivery

   - release kinetics: immediate - sustained - delayed

   - reservoir systems

   - matrix systems

   - osmotic control

Slides

Selected chapters from textbooks

 

Evaluation

Evaluation: Basics of Pharmaceutical Technology (B-KUL-H2E19a)

Type : Exam during the examination period
Description of evaluation : Written
Type of questions : Open questions
Learning material : List of formulas