Basics of Pharmaceutical Technology (B-KUL-H0E19A)
Aims
The aim of this course is to provide students with a non-pharmaceutical background a comprehensive introduction to the fundamental concepts and underlying scientific principles of drug formulation, pharmaceutical process development, drug delivery and drug targeting.
Is included in these courses of study
Activities
3 ects. Basics of Pharmaceutical Technology (B-KUL-H0E19a)
Content
1. Introduction to physicochemical and biopharmaceutical principles underlying drug formulation
- principles of drug absorption
- drug dissolution
- bioavailability and bioequivalence
- principles of pharmacokinetics
- transport of drugs across epithelia
2. Disperse systems
- introductory principles of rheology
- suspensions
- emulsions
- gels
3. Formulation strategies for poorly soluble drugs
- micro- and nanoparticles
- cyclodextrine complexes
- amorphous solid dispersions
- lipid based drug delivery systems
- cocrystals
- colsolvency
4. Agglomeration processes
- granulation
- spray drying
- extrusion-spheronization
5. Principles of controlled drug delivery
- release kinetics: immediate - sustained - delayed
- reservoir systems
- matrix systems
- osmotic control
Course material
Slides
Selected chapters from textbooks