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Characterization of Biomolecular Interactions at Surfaces (B-KUL-H08R9B)

3 ECTSEnglishFirst termCannot be taken as part of an examination contractCannot be taken as part of a credit contract
N.
Extern Université Grenoble Alpes
POC Nanowetenschappen en nanotechnologie

Aims

The aim of this course is to introduce the main techniques used to characterize molecular and more specifically bio-molecular interactions with or at surfaces It will present, discuss and compare a choice of techniques, and insist on the advantages and drawbacks of the different techniques. This course is accessible to biologists, chemists and physicists.

Is included in these courses of study

Activities

3 ects. Characterization of Biomolecular Interactions at Surfaces (B-KUL-H08R9a)

3 ECTSEnglishFormat: Lecture-practicalFirst term
N.
POC Nanowetenschappen en nanotechnologie

Content

Electron microscopy

  • Why use electrons for imaging and how ?
  • Scanning Electron Microscopy
  • Transmission Electron Microscopy

 

Surface analysis techniques

  • Main principles of radiation –matter interaction
  • X-ray Photoelectron Spectroscopy (XPS)
  • Auger spectroscopy
  • Synchrotron radiation as source of high brilliant X-rays
  • X-Ray Absorption spectroscopy
  • Rutherford Back Scattering (RBS)
  • Resonance Nuclear Analysis (NRA)
  • Secondary Ion Mass Spectroscopy (SIMS)
  • Total X-Ray Fluorescence (TXRF)
  • X-Ray reflectivity

 

Local probe microscopy technics (STM, AFM)

  • Applications on Physics, Chemistry,  Biology exemples
  • Different modes: contact, tapping, EFM Kelvin probe/magnetic
  • Artifacs
  • Pictures reading : what type of informations can we get out of the datas ?

Course material

Text book, articles and literature, syllabus, slides.

Evaluation

Evaluation: Characterization of Biomolecular Interactions at Surfaces (B-KUL-H28R9b)

Type : Exam during the examination period
Description of evaluation : Written