Required in stage
Optional in stage
First term
Second term
Both terms
This year
Next year
Alternating years
External
Prerequisites
Taught by
Language of instruction
Duration
LevelRadiopharmaceutical Analysis (B-KUL-K08C7A)
Aims
To provide the students with a thorough knowledge of and insight in the principles, the potential application and the use of different instruments for measurement of radioactivity, especially in the framework of development and analysis of drugs and biochemical research.
Previous knowledge
No specific foreknowledge is required, except for some elements of physics which are taught in the bachelor degree.
Course material
Syllabus
Toledo / e-platform
Activities
3.0 ects. Radiopharmaceutical Analysis (B-KUL-K08C7a)
Content
Overview of different kinds of radiation detectors:
- gas filled detectors
- scintillation detectors: thallium activated sodium iodide detectors; newer solid state detectors (BGO and LSO);
liquid scintillation detection, plastic scintillators;
- semiconductor detectors
- autoradiography: film detection, wire chambers, phosphorescent detectors, micro-autoradiography and applications in
biochemical research
- Dosimeters for radiation protection (TLD, film dosimeters)
Selection and application of different kinds of detectors: activity meter, spectrometer, rate meter, scaler-timer, dosimeter
Gamma camera for animal research
Measurement of tritium and carbon-14: quenching, oxidisers, scintillation cocktails, measurement of beta radiation in urine, faeces, blood, bone, tissues
Detection of radiation in chromatographic analysis (thin-layer chromatography, high pressure liquid chromatography, gas chromatography
Measurement of radioactivity in airFactors affecting accuracy of radiation detection
Description of learning activities
Attending courses
Excersises: individual preparation of certain parts with further explanation during couses
Course material
syllabus
illustrations of measuring devices on Toledo
