The goal of this course is to provide the students with insight into the mode of action of different classes of drugs. It is neither the intension nor a possibility to be exhaustive. Nevertheless, this course aims to provide a framework within which new information can readily be placed and assimilated. Finally, a brief introduction will be given to the process of development, evaluation and testing, registration and, finally refunding of new drugs.
Cell biology, biochemistry, pathophysiology, basics of pathology and anatomy are essential prior knowledge for this course.
Articles and literature
Slides, transparencies, courseware
Toledo / e-platform
Order of Enrolment
You may only take this course if you comply with the prerequisites. Prerequisites can be strict or flexible, or can imply simultaneity. A degree level can be also be a prerequisite.
STRICT: You may only take this course if you have passed or applied tolerance for the courses for which this condition is set.
FLEXIBEL: You may only take this course if you have previously taken the courses for which this condition is set.
SIMULTANEOUS: You may only take this course if you also take the courses for which this condition is set (or have taken them previously).
DEGREE: You may only take this course if you have obtained this degree level.
The codes of the course units mentioned above correspond to the following course descriptions:
This course unit is a prerequisite for taking the following course units:
E03N9A : Pharmaceutical Medicine
E07U2A : Toxicology
Is also included in other courses
- Master of Biomedical Sciences 120 ects.
The following subjects will be covered:
Introduction to pharmacology:
Development (incl. notions of 'rational drug design'); evaluation and testing of new drugs (e.g. bioassay); brief overview of registration procedure and refunding
insights in kinetic processes of absorption, distribution and elimination
biotransformation/metabolism of drugs
Pharmacodynamics and receptors (basics since receptor mechanisms are addressed extensively in cell biology and biochemistry)
toxicity of drugs: mechanisms
Pharmacology, with special attention to mechanisms of action of the different groups of pharmacological agents (no individual drugs will be discussed) related to:
the autonomous and peripheral nervous system
the central nervous system
the cardiovascular system
the endocrine system
pain, fever and inflammation
Cytostatics, biotechnological drugs (monoclonal antibodies)
Description of learning activities
Active participation and taking notes is expected during the lectures. Prints of the slides (available via Toledo) can facilitate note taking.
Toledo with literature and references
Toledo will have a list of all course material that is expected knowledge
Each student will do the complete exam with one of the course lecturers
Oral with written preparation: 4 questions
The questions will include:
1. An open question.
2. Explanation of a case report or an article concerning the use of (a) drug(s).
3. Two questions with different parts/topics for which situation/explanation/justification of the answer is expected.
A minimum of 60 minutes is provided for written preparation of the exam. Afterwards the students can present themselves to the designated examiner for the oral part of the exam.
All documents (including preparatory documents) have to be handed over to the examiner or the observer.
Third examination period
The evaluation during the third exam period is the same as above.